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The powerful ion exchanger in the Cartridge removes calcification in the water to prevent white dust often created by ultrasonic systems.  It lasts up to three months, depending on the water's hardness.  Suitable for most ultrasonic humidifiers with a standard tank cover. The Water Cube keeps humidifiers fresh. It works in ultrasonics, evaporators, and air washers. Lasts up to one year (12 months). Suitable for use with most humidifiers made by other manufacturers.